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Cat. No. Product Name Information
PC-35127

NCT-506

ALDH1A1 inhibitor

NCT-506 (NCT506) is a potent, selective, orally available ALDH1A1 inhibitor with IC50 of 7 nM (hALDH1A1), exhibits high specificity over other ALDH isozymes and unrelated dehydrogenases.
PC-35126

NCT-505

ALDH1A1 inhibitor

NCT-505 (NCT505) is a potent, selective, orally available ALDH1A1 inhibitor with IC50 of 7 nM (hALDH1A1), exhibits high specificity over other ALDH isozymes and unrelated dehydrogenases.
PC-61351

DIMATE

ALDH1 inhibitor

DIMATE is a novel irreversible, competitive, isoform-specific ALDH1 inhibitor, displays cytotoxic activity on human AML cell lines with IC50 of 1-15 uM.
PC-61349

CVT-10216

ALDH2 inhibitor

CVT-10216 (GS-455534) is a potent, highly selective, reversible inhibitor of ALDH2 with IC50 of 29 nM, shows no significant inhibition for ALDH1 (IC50=1,300 nM).
PC-70323

Aldi-6

ALDH inhibitor

Aldi-6 is a novel small molecule ALDH inhibitor with IC50 of 600 nM, 800 nM and 1000 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively.
PC-60168

WIN 18446

ALDH1A2 inhibitor

WIN 18446 is a potent, covalent, orally active ALDH1A2 inhibitor with IC50 of 0.3 uM.
PC-45563

Alda-1

ALDH2 activator

Alda-1 is a small-molecule activator of ALDH2, particularly effective activator of ALDH2*2 (EC50= 20 uM, increases the activity of the mutant, ALDH2*2 (11-fold).
PC-45551

NCT-501

ALDH1A1 inhibitor

NCT-501 (NCT501) is a potent and highly selective inhibitor of ALDH1A1 with IC50 of 40 nM for hALDH1A1.

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