| Cat. No. |
Product Name |
Information |
| PC-35380 |
ALDH3A1 inhibitor EN40
ALDH3A1 inhibitor
|
ALDH3A1 inhibitor EN40 is a potent and selective, covalent, in vivo-active inhibitor of ALDH3A1 with IC50 of 2 uM, demonstrates no activity against ALDH1A3 and ALDH6A1 at 30 uM. |
| PC-35128 |
NCT-507
ALDH1A1 inhibitor
|
NCT-507 (NCT507) is a potent, selective, orally available ALDH1A1 inhibitor with IC50 of 7 nM (hALDH1A1), exhibits high specificity over other ALDH isozymes and unrelated dehydrogenases. |
| PC-35127 |
NCT-506
ALDH1A1 inhibitor
|
NCT-506 (NCT506) is a potent, selective, orally available ALDH1A1 inhibitor with IC50 of 7 nM (hALDH1A1), exhibits high specificity over other ALDH isozymes and unrelated dehydrogenases. |
| PC-35126 |
NCT-505
ALDH1A1 inhibitor
|
NCT-505 (NCT505) is a potent, selective, orally available ALDH1A1 inhibitor with IC50 of 7 nM (hALDH1A1), exhibits high specificity over other ALDH isozymes and unrelated dehydrogenases. |
| PC-61351 |
DIMATE
ALDH1 inhibitor
|
DIMATE is a novel irreversible, competitive, isoform-specific ALDH1 inhibitor, displays cytotoxic activity on human AML cell lines with IC50 of 1-15 uM. |
| PC-61349 |
CVT-10216
ALDH2 inhibitor
|
CVT-10216 (GS-455534) is a potent, highly selective, reversible inhibitor of ALDH2 with IC50 of 29 nM, shows no significant inhibition for ALDH1 (IC50=1,300 nM). |
| PC-70323 |
Aldi-6
ALDH inhibitor
|
Aldi-6 is a novel small molecule ALDH inhibitor with IC50 of 600 nM, 800 nM and 1000 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively. |
| PC-60168 |
WIN 18446
ALDH1A2 inhibitor
|
WIN 18446 is a potent, covalent, orally active ALDH1A2 inhibitor with IC50 of 0.3 uM. |
| PC-45563 |
Alda-1
ALDH2 activator
|
Alda-1 is a small-molecule activator of ALDH2, particularly effective activator of ALDH2*2 (EC50= 20 uM, increases the activity of the mutant, ALDH2*2 (11-fold). |
| PC-45551 |
NCT-501
ALDH1A1 inhibitor
|
NCT-501 (NCT501) is a potent and highly selective inhibitor of ALDH1A1 with IC50 of 40 nM for hALDH1A1. |
| PC-26957 |
YG1702
ALDH18A1 inhibitor
|
YG1702 is a potent, specific aldehyde dehydrogenase family 18 member A1 (ALDH18A1) inhibitor with association constant (Ka) of 0.589 uM in ITC assays. |
| PC-26953 |
NCATS-SM0708
ALDH3A1 inhibitor
|
NCATS-SM0708 is a potent, selective Aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor with biochemical IC50 of 13.62 nM in enzymatic assays, and cellular IC50 of 3.84 nM in ALDEFLUOR assays. |
