Chemical Structure : Aldi-6
CAS No.: 2138-34-3
Catalog No.: PC-70323Not For Human Use, Lab Use Only.
Aldi-6 is a novel small molecule ALDH inhibitor with IC50 of 600 nM, 800 nM and 1000 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively.
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Aldi-6 is a novel small molecule ALDH inhibitor with IC50 of 600 nM, 800 nM and 1000 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively.
Aldi-6 decreases SCC4 cells viability, sensitizes HNSCC cells to cisplatin.
The combination of Aldi-6 and cisplatin causes a greater reduction in tumor burden in vivo than cisplatin alone.
M.Wt | 256.143 | |
Formula | C11H14BrNO | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-(4-bromophenyl)-3-(dimethylamino)propan-1-one |
1. Kim J, et al. Oncotarget. 2017 Apr 10. doi: 10.18632/oncotarget.17017.
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