Aldi-6 | ALDH inhibitor | Probechem Biochemicals

Chemical Structure : Aldi-6

CAS No.: 2138-34-3

Aldi-6 (Aldi6)

Catalog No.: PC-70323Not For Human Use, Lab Use Only.

Aldi-6 is a novel small molecule ALDH inhibitor with IC50 of 600 nM, 800 nM and 1000 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively.

Packing	Price	Stock
25 mg	$128	In stock
50 mg	$188	In stock
100 mg	$328	In stock
200 mg		Get quote
1 g		Get quote

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Biological Activity

Aldi-6 is a novel small molecule ALDH inhibitor with IC50 of 600 nM, 800 nM and 1000 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively.
Aldi-6 decreases SCC4 cells viability, sensitizes HNSCC cells to cisplatin.
The combination of Aldi-6 and cisplatin causes a greater reduction in tumor burden in vivo than cisplatin alone.

Physicochemical Properties

M.Wt	256.143
Formula	C11H14BrNO
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-bromophenyl)-3-(dimethylamino)propan-1-one

References

1. Kim J, et al. Oncotarget. 2017 Apr 10. doi: 10.18632/oncotarget.17017.

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Aldi-6 (Aldi6)

Biological Activity

Physicochemical Properties

References

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