WIN 18446 | ALDH1A2 inhibitor | Probechem Biochemicals

Chemical Structure : WIN 18446

CAS No.: 1477-57-2

WIN 18446 (WIN18446)

Catalog No.: PC-60168Not For Human Use, Lab Use Only.

WIN 18446 is a potent, covalent, orally active ALDH1A2 inhibitor with IC50 of 0.3 uM.

Packing	Price	Stock
25 mg	$58	In stock
50 mg	$88	In stock
100 mg	$128	In stock
250 mg		Get quote

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Biological Activity

WIN 18446 is a potent, covalent, orally active ALDH1A2 inhibitor with IC50 of 0.3 uM.
WIN 18446 potently inhibits spermatogenesis and causes infertility in vivo by inhibiting retinoic acid synthesis.

Physicochemical Properties

M.Wt	366.11
Formula	C12H20Cl4N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N,N'-1,8-Octanediylbis(2,2-dichloroacetamide)

References

1. Amory JK, et al. J Androl. 2011 Jan-Feb;32(1):111-9.

2. Paik J, et al. J Biol Chem. 2014 May 23;289(21):15104-17.

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WIN 18446 (WIN18446)

Biological Activity

Physicochemical Properties

References

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