Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : CVT-10216
CAS No.: 1005334-57-5
Catalog No.: PC-61349Not For Human Use, Lab Use Only.
CVT-10216 (CVT10216) is a potent, highly selective, reversible inhibitor of ALDH2 with IC50 of 29 nM, shows no significant inhibition for ALDH1 (IC50=1,300 nM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $148 | In stock | |
| 10 mg | $228 | In stock | |
| 25 mg | $398 | In stock | |
| 50 mg | $598 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
CVT-10216 (CVT10216) is a potent, highly selective, reversible inhibitor of ALDH2 with IC50 of 29 nM, shows no significant inhibition for ALDH1 (IC50=1,300 nM).
CVT-10216 demonstrates therapeutic potential to reduce excessive drinking and to suppress relapse in abstinent alcoholics.
CVT-10216 also shows both anxiolytic and antidipsotropic properties in rats.
CVT-10216 selectively suppresses binge eating of palatable food and attenuates dopamine release in the accumbens of sugar-bingeing rats.
| M.Wt | 465.5 | |
| Formula | C24H19NO7S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-1-benzopyran-7-yl]oxy]methyl]benzoic acid |
|
1. Arolfo MP, et al. Alcohol Clin Exp Res. 2009 Nov;33(11):1935-44.
2. Overstreet DH, et al. Pharmacol Biochem Behav. 2009 Dec;94(2):255-61.
3. Bocarsly ME, et al. Behav Pharmacol. 2014 Apr;25(2):147-57.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
