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Chemical Structure : NCT-501
CAS No.: 1802088-50-1
Catalog No.: PC-45551Not For Human Use, Lab Use Only.
NCT-501 (NCT501) is a potent and highly selective inhibitor of ALDH1A1 with IC50 of 40 nM for hALDH1A1.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $148 | In stock | |
| 10 mg | $228 | In stock | |
| 25 mg | $398 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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NCT-501 (NCT501) is a potent and highly selective inhibitor of ALDH1A1 with IC50 of 40 nM for hALDH1A1.
NCT-501 exhibits high selectivity against ALDH1A1 over ALDH3A1, ALDH1B1, ALDH2 isozymes and other dehydrogenases such as HPGD and HSD17β4.
NCT-501 has excellent pharmacokinetics and in vitro ADME profiles.
| M.Wt | 416.5172 | |
| Formula | C21H32N6O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 28 mg/mL |
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| Chemical Name/SMILES |
1H-Purine-2,6-dione, 8-[[4-(cyclopropylcarbonyl)-1-piperazinyl]methyl]-3,7-dihydro-1,3-dimethyl-7-(3-methylbutyl)- |
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1. Yang SM, et al. J Med Chem. 2015 Aug 13;58(15):5967-78.
2. Kulsum S, et al. Mol Carcinog. 2017 Feb;56(2):694-711.
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