NCT-501 |CAS:1802088-50-1 Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Aldehyde Dehydrogenase (ALDH)-NCT-501

Chemical Structure : NCT-501

CAS No.: 1802088-50-1

NCT-501 (NCT501, NCT 501)

Catalog No.: PC-45551Not For Human Use, Lab Use Only.

NCT-501 (NCT501) is a potent and highly selective inhibitor of ALDH1A1 with IC50 of 40 nM for hALDH1A1.

Packing	Price	Stock
5 mg	$148	In stock
10 mg	$228	In stock
25 mg	$398	In stock
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

NCT-501 (NCT501) is a potent and highly selective inhibitor of ALDH1A1 with IC50 of 40 nM for hALDH1A1.
NCT-501 exhibits high selectivity against ALDH1A1 over ALDH3A1, ALDH1B1, ALDH2 isozymes and other dehydrogenases such as HPGD and HSD17β4.
NCT-501 has excellent pharmacokinetics and in vitro ADME profiles.

Physicochemical Properties

M.Wt	416.5172
Formula	C21H32N6O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: ≥ 28 mg/mL
Chemical Name/SMILES	1H-Purine-2,6-dione, 8-[[4-(cyclopropylcarbonyl)-1-piperazinyl]methyl]-3,7-dihydro-1,3-dimethyl-7-(3-methylbutyl)-

References

1. Yang SM, et al. J Med Chem. 2015 Aug 13;58(15):5967-78.

2. Kulsum S, et al. Mol Carcinog. 2017 Feb;56(2):694-711.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

NCT-501 (NCT501, NCT 501)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.