| Cat. No. |
Product Name |
Information |
| PC-49053 |
IGUANA-1
ALDH1B1 inhibitor
|
IGUANA-1 is a potent, isoform-selective inhibitor of aldehyde dehydrogenase ALDH1B1 with IC50 of 30 nM. |
| PC-72799 |
MCI-INI-3
ALDH1A3 inhibitor
|
MCI-INI-3 is a potent, selective, competitive inhibitor of ALDH1A3 (Ki=0.55 uM, shows poor inhibitory effect on the structurally related isoform ALDH1A1 (>140-fold selectivity). |
| PC-72688 |
Dichloro-all-trans-retinone
ALDH1A inhibitor
|
Dichloro-all-trans-retinone (DAR) is an irreversible inhibitor of retinaldehyde dehydrogenase (RALDH/ALDH1A) with IC50 of 434/55/161 nM for RALDH1/RALDH2/RALDH3. |
| PC-38166 |
KS100
ALDH inhibitor
|
ALDH inhibitor KS100 (KS100) is a novel, potent, multi-isoform ALDH inhibitor with IC50 of 207/1410/240 nM for ALDH1A1/ALDH2/ALDH3A1, respectively. |
| PC-36129 |
ALDH1A inhibitor 673A
ALDH1A inhibitor
|
ALDH1A inhibitor 673A (ALDH1Ai 673A) is a potent, selective, pan-ALDH1A inhibitor with IC50 of 246, 230 and 348 nM for ALDH1A1, ALDH1A2 and ALDH1A3, respectively. |
| PC-35950 |
NCT-505 free base
ALDH1A1 inhibitor
|
NCT-505 free base (NCT505) is a potent, selective, orally available ALDH1A1 inhibitor with IC50 of 7 nM (hALDH1A1), exhibits high specificity over other ALDH isozymes and unrelated dehydrogenases. |
| PC-35381 |
DKM 3-42
ALDH3A1 inhibitor
|
DKM 3-42 is a selective, covalent, in vivo-active ALDH3A1 inhibitor with IC50 of 50 uM against purified human ALDH3A1, targets ALDH3A1 catalytic cysteine, impairs both in situ and in vivo lung cancer pathogenicity. |
| PC-35380 |
ALDH3A1 inhibitor EN40
ALDH3A1 inhibitor
|
ALDH3A1 inhibitor EN40 is a potent and selective, covalent, in vivo-active inhibitor of ALDH3A1 with IC50 of 2 uM, demonstrates no activity against ALDH1A3 and ALDH6A1 at 30 uM. |
| PC-35128 |
NCT-507
ALDH1A1 inhibitor
|
NCT-507 (NCT507) is a potent, selective, orally available ALDH1A1 inhibitor with IC50 of 7 nM (hALDH1A1), exhibits high specificity over other ALDH isozymes and unrelated dehydrogenases. |
| PC-35127 |
NCT-506
ALDH1A1 inhibitor
|
NCT-506 (NCT506) is a potent, selective, orally available ALDH1A1 inhibitor with IC50 of 7 nM (hALDH1A1), exhibits high specificity over other ALDH isozymes and unrelated dehydrogenases. |
| PC-35126 |
NCT-505
ALDH1A1 inhibitor
|
NCT-505 (NCT505) is a potent, selective, orally available ALDH1A1 inhibitor with IC50 of 7 nM (hALDH1A1), exhibits high specificity over other ALDH isozymes and unrelated dehydrogenases. |
| PC-61351 |
DIMATE
ALDH1 inhibitor
|
DIMATE is a novel irreversible, competitive, isoform-specific ALDH1 inhibitor, displays cytotoxic activity on human AML cell lines with IC50 of 1-15 uM. |
