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Chemical Structure : LEI-945
Catalog No.: PC-20139Not For Human Use, Lab Use Only.
LEI-945 (LEI 945) is a first-in-class probe that enables profiling retinaldehyde dehydrogenases (ALDHs) in cancer cells.
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LEI-945 (LEI 945) is a first-in-class probe that enables profiling retinaldehyde dehydrogenases (ALDHs) in cancer cells.
LEI-945 can be used for the activity-based protein profiling (ABPP) of retinaldehyde dehydrogenases, ALDH1A1, ALDH1A2 and ALDH1A3.
LEI-945 enables the quantification of ALDH isozyme activities in a panel of cancer cell lines via both fluorescence and chemical proteomic approaches.
| M.Wt | 364.53 | |
| Formula | C25H32O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Koenders STA, et al. ACS Cent Sci. 2019 Dec 26;5(12):1965-1974.
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