MCI-INI-3 | ALDH1A3 inhibitor | Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Aldehyde Dehydrogenase (ALDH)-MCI-INI-3

Chemical Structure : MCI-INI-3

MCI-INI-3 (ALDH1A3 inhibitor)

Catalog No.: PC-72799Not For Human Use, Lab Use Only.

MCI-INI-3 is a potent, selective, competitive inhibitor of ALDH1A3 (Ki=0.55 uM, shows poor inhibitory effect on the structurally related isoform ALDH1A1 (>140-fold selectivity).

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MCI-INI-3 is a potent, selective, competitive inhibitor of ALDH1A3 (Ki=0.55 uM), shows poor inhibitory effect on the structurally related isoform ALDH1A1 (>140-fold selectivity).
MCI-INI-3 also displays on inhibition against six isoforms of ALDH (ALDH16A1, ALDH7A1, ALDH9A1, ALDH2, ALDH1B1, ALDH18A1).
MCI-INI-3 demonstrates selective binding to ALDH1A3 in glioma stem cell lysates, inhibits ALDH activity and affects RA synthesis in cells.

Physicochemical Properties

M.Wt	373.368
Formula	C21H15N3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	methyl 5-(benzo[d][1,3]dioxol-5-yl)-2-phenylpyrazolo[1,5-a]pyrimidine-7-carboxylate

References

1. Jianfeng Li, et al. Commun Biol. 2021 Dec 21;4(1):1420.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com