IGUANA-1 | ALDH1B1 inhibitor | Probechem Biochemicals

Chemical Structure : IGUANA-1

IGUANA-1 (IGUANA 1)

Catalog No.: PC-49053Not For Human Use, Lab Use Only.

IGUANA-1 is a potent, isoform-selective inhibitor of aldehyde dehydrogenase ALDH1B1, exhibits proteome-wide target specificity, and selectively blocks the growth of colon cancer spheroids and organoids.

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Biological Activity

IGUANA-1 is a potent, isoform-selective inhibitor of aldehyde dehydrogenase ALDH1B1, exhibits proteome-wide target specificity, and selectively blocks the growth of colon cancer spheroids and organoids.

Physicochemical Properties

M.Wt	445.947
Formula	C26H24ClN3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(4-chloro-2-methoxyphenyl)-1-(2'-methoxy-[1,1'-biphenyl]-4-yl)-1,5,6,7-tetrahydroimidazo[1,2-a]pyrimidine

References

1. Feng Z, et al. Nat Chem Biol. 2022 Jul 4. doi: 10.1038/s41589-022-01048-w.

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IGUANA-1 (IGUANA 1)

Biological Activity

Physicochemical Properties

References

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