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IGUANA-1

Chemical Structure : IGUANA-1

CAS No.: 2756014-24-9

IGUANA-1

Catalog No.: PC-49053Not For Human Use, Lab Use Only.

IGUANA-1 is a potent, isoform-selective inhibitor of aldehyde dehydrogenase ALDH1B1, exhibits proteome-wide target specificity, and selectively blocks the growth of colon cancer spheroids and organoids.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

IGUANA-1 is a potent, isoform-selective inhibitor of aldehyde dehydrogenase ALDH1B1, exhibits proteome-wide target specificity, and selectively blocks the growth of colon cancer spheroids and organoids.

Physicochemical Properties

M.Wt 445.947
Formula C26H24ClN3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(4-chloro-2-methoxyphenyl)-1-(2'-methoxy-[1,1'-biphenyl]-4-yl)-1,5,6,7-tetrahydroimidazo[1,2-a]pyrimidine

References

1. Feng Z, et al. Nat Chem Biol. 2022 Jul 4. doi: 10.1038/s41589-022-01048-w.

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