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BRD1172

Chemical Structure : BRD1172

CAS No.: 1597438-86-2

BRD1172 (BRD-1172)

Catalog No.: PC-62878Not For Human Use, Lab Use Only.

BRD1172 is a highly selective, potent, reversible, ATP-competitive GSK3 inhibitor with IC50 of 3 nM/10 nM for GSK3α/GSK3β, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BRD1172 is a highly selective, potent, reversible, ATP-competitive GSK3 inhibitor with IC50 of 3 nM/10 nM for GSK3α/GSK3β, respectively.

    Physicochemical Properties

    M.Wt 391.394
    Formula C20H20F3N3O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (4R)-4-(2-methoxyphenyl)-7,7-dimethyl-3-(trifluoromethyl)-2,4,6,8-tetrahydro-1H-pyrazolo[3,4-b]quinolin-5-one

    References

    1. Wagner FF, et al. ACS Chem Biol. 2016 Jul 15;11(7):1952-63.

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