Chemical Structure : Bikinin
CAS No.: 188011-69-0
Catalog No.: PC-43092Not For Human Use, Lab Use Only.
Bikinin (Abrasin) is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor, binds and inhibits Arabidopsis thaliana GSK3-like kinases.
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Bikinin (Abrasin) is a plant GSK-3/Shaggy-like kinases inhibitor that activates brassinosteroid (BR) signaling downstream of the BR receptor, binds and inhibits Arabidopsis thaliana GSK3-like kinases.
Bikinin interferes directly with BIN2 kinase activity, also strongly inhibited the activity of the group I Arabidopsis GSK3 subfamilies, but not the ASKβ, ASKδ, and other Arabidopsis Ser/Thr kinases (AtMPK4, AtMPK6, and AtAURORA1).
Bikinin inhibits the SnRK2.3 kinase activity and its T180 phosphorylation in vivo.
M.Wt | 273.0834 | |
Formula | C9H9BrN2O3 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 42 mg/mL |
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Chemical Name/SMILES |
Butanoic acid, 4-[(5-bromo-2-pyridinyl)amino]-4-oxo- |
1. De Rybel B, et al. Chem Biol. 2009 Jun 26;16(6):594-604.
2. Cai Z, et al. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9651-6.
3. Rozhon W, et al. BMC Plant Biol. 2014 Jun 19;14:172.
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