BRD0320 | GSK3α/β inhibitor | Probechem Biochemicals

Chemical Structure : BRD0320

Catalog No.: PC-22892Not For Human Use, Lab Use Only.

BRD0320 is a potent, dual inhibitor of GSK3α/β with Kd of 1.2/1.9 uM respectively.

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Biological Activity

BRD0320 is a potent, dual inhibitor of GSK3α/β with Kd of 1.2/1.9 uM, IC50 of 8/5 nM respectively.

M.Wt	365.45
Formula	C22H24FN3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-cyclopropyl-4-(3-fluorophenyl)-4,7,7-trimethyl-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one

1. Florence F Wagner, et al. Sci Transl Med. 2018 Mar 7;10(431):eaam8460.

2. Mohamed H Yousef, et al. Mol Neurobiol. 2022 Sep;59(9):5591-5611.