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Pentagalloylglucose

Chemical Structure : Pentagalloylglucose

CAS No.: 14937-32-7

Pentagalloylglucose (Penta-O-galloyl-β-D-glucose, 1,2,3,4,6-Pentagalloyl glucose)

Catalog No.: PC-25724Not For Human Use, Lab Use Only.

Pentagalloylglucose is an orally active gallic tannin compound, induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway, inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids, also is a specific TRMT61A inhibitor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Pentagalloylglucose is an orally active gallic tannin compound, induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway, inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids, also is a specific TRMT61A inhibitor.

Physicochemical Properties

M.Wt 940.68
Formula C41H32O26
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,3R,4S,5R,6R)-6-(((3,4,5-Trihydroxybenzoyl)oxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetrakis(3,4,5-trihydroxybenzoate)

References

1. Zhang X, et al. Cancer Commun (Lond). 2025 Oct 16.

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