GSK3 inhibitor 117

Chemical Structure : GSK3 inhibitor 117

Catalog No.: PC-20191Not For Human Use, Lab Use Only.

GSK3 inhibitor 117 is a novel selective GSK-3 inhibitor, shows cytotoxicity against AML in vitro and in vivo.

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Biological Activity

GSK3 inhibitor 117 is a novel selective GSK-3 inhibitor, shows cytotoxicity against AML in vitro and in vivo.

M.Wt	444.85
Formula	C18H13ClN6O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Chloro-N-[4-[5-[[[5-(1-oxido-4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]methyl]-1,2,4-oxadiazol-3-yl]phenyl]acetamide

1. Patent WO2016061344 A1.

2. Reshmi Parameswaran, et al. Nat Commun. 2016 Apr 4;7:11154.