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Methyliodobikinin

Chemical Structure : Methyliodobikinin

CAS No.: 1186336-04-8

Methyliodobikinin

Catalog No.: PC-63239Not For Human Use, Lab Use Only.

Methyliodobikinin is a potent bikinin-like inhibitor targeting GSK3/Shaggy-like kinase, shows improved cell permeability, highly potent in vivo although it had lower activity in vitro.

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    Biological Activity

    Methyliodobikinin is a potent bikinin-like inhibitor targeting GSK3/Shaggy-like kinase, shows improved cell permeability, highly potent in vivo although it had lower activity in vitro.
    Methyliodobikinin activates brassinosteroid (BR) signalling and mimic BR action.
    Methyliodobikinin 3.4 times more active in vivo than bikinin.

    Physicochemical Properties

    M.Wt 334.113
    Formula C10H11IN2O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    Methyl 4-((5-iodopyridin-2-yl)amino)-4-oxobutanoate

    References

    1. Rozhon W, et al. BMC Plant Biol. 2014 Jun 19;14:172.

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