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Cat. No. Product Name Information
PC-22109

GSK_WRN3

WRN helicase inhibitor

GSK_WRN3 (WRNi, GSK-WRN3) is a potent and highly selective WRN helicase covalent inhibitor with biochemical pIC50 of 8.6, covalently targets WRN Cys727 residue.
PC-22108

GSK_WRN2

WRN helicase inhibitor

GSK_WRN2 is a potent and highly selective WRN helicase covalent inhibitor with biochemical pIC50 of 6.5, covalently targets WRN Cys727 residue.
PC-22107

GSK_WRN1

WRN helicase inhibitor

GSK_WRN1 is a potent and highly selective WRN helicase covalent inhibitor with biochemical pIC50 of 5.8, covalently targets WRN Cys727 residue.
PC-20533

MTH1 inhibitor AZ19

MTH1 inhibitor

MTH1 inhibitor AZ19 is a highly potent MTH1 inhibitor with IC50 of 0.9 nM and Kd of 0.5 nM, displays EC50 of 7 nM in whole cell thermal stability assay in K562 cells.

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