Cat. No. |
Product Name |
Information |
PC-22109 |
GSK_WRN3
WRN helicase inhibitor
|
GSK_WRN3 (WRNi, GSK-WRN3) is a potent and highly selective WRN helicase covalent inhibitor with biochemical pIC50 of 8.6, covalently targets WRN Cys727 residue. |
PC-22108 |
GSK_WRN2
WRN helicase inhibitor
|
GSK_WRN2 is a potent and highly selective WRN helicase covalent inhibitor with biochemical pIC50 of 6.5, covalently targets WRN Cys727 residue. |
PC-22107 |
GSK_WRN1
WRN helicase inhibitor
|
GSK_WRN1 is a potent and highly selective WRN helicase covalent inhibitor with biochemical pIC50 of 5.8, covalently targets WRN Cys727 residue. |
PC-20533 |
MTH1 inhibitor AZ19
MTH1 inhibitor
|
MTH1 inhibitor AZ19 is a highly potent MTH1 inhibitor with IC50 of 0.9 nM and Kd of 0.5 nM, displays EC50 of 7 nM in whole cell thermal stability assay in K562 cells. |