Cat. No. |
Product Name |
Information |
PC-35174 |
MLAF50
|
MLAF50 is the first small-molecule inhibitor of the REV1 UBM2-Ubiquitin interaction, directly binds to REV1 UBM2 with Kd of 37 uM in SPR assays. |
PC-62839 |
RAD51-IN-17
|
RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines. |
PC-61926 |
PFM01
|
PFM01 (SML1735) is a small molecule that specifically inhibits endonuclease, but not exonuclease activity of MRE11, inhibits dsDNA end resection in A549 cells with IC50 of 50-75 uM, blocks the ssDNA-binding path toward the catalytic metal ions and disrupts endonuclease activity.. |
PC-61924 |
6-Hydroxy-DL-DOPA
|
6-Hydroxy-DL-DOPA is a small-molecule that disrupts with RAD52 oligomerization, inhibits ssDNA binding by RAD52 with IC50 of 1.1 uM and by RAD52 (1 209) with IC50 of 1.6 uM. |
PC-61921 |
NSC 19630
|
NSC 19630 (MIRA-1) is a potent, selective Werner syndrome helicase (WRN helicase) with IC50 of 20 uM. |
PC-61920 |
NSC 617145
|
NSC 617145 is a novel small-molecule, selective inhibitor of WRN helicase with IC50 of 230 nM. |
PC-61900 |
Rev1-IN-5
|
Rev1-IN-5 is a small molecule inhibitor of the C-terminal domain of Rev1 and the Rev1-interacting region protein-protein interaction (Rev1-CT/RIR PPI) with IC50 of 2.5 uM. |