| Cat. No. |
Product Name |
Information |
| PC-61921 |
NSC 19630
WRN helicase inhibitor
|
NSC 19630 (MIRA-1) is a potent, selective Werner syndrome helicase (WRN helicase) with IC50 of 20 uM. |
| PC-61920 |
NSC 617145
WRN inhibitor
|
NSC 617145 is a novel small-molecule, selective inhibitor of WRN helicase with IC50 of 230 nM. |
| PC-61900 |
Rev1-IN-5
Rev1 inhibitor
|
Rev1-IN-5 is a small molecule inhibitor of the C-terminal domain of Rev1 and the Rev1-interacting region protein-protein interaction (Rev1-CT/RIR PPI) with IC50 of 2.5 uM. |
| PC-61067 |
BAY-707
MTH1 inhibitor
|
BAY-707 is a highly potent, selective and substrate-competitive inhibitor of MTH1 (NUDT1) with IC50 of 2.3 nM. |
| PC-42079 |
HUHS-015
PCA-1/ALKBH3 inhibitor
|
HUHS-015 (HUHS015) is a potent, orally active prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitor with IC50 of 0.67 uM. |
| PC-43226 |
TH-588
MTH1 inhibitor
|
TH-588 is a potent and selective inhibitor of MTH1 (NUDT1) protein with IC50 of 5 nM. |
| PC-45104 |
TH-287
MTH1 inhibitor
|
TH-287 is a potent and selective inhibitor of MTH1 (NUDT1) protein with IC50 of 0.8 nM. |
| PC-22774 |
HDGFRP2 PWWP domain inhibitor BBP
HDGFRP2 PWWP inhibitor
|
BBP is a small molecule inhibitor of the hepatoma-derived growth factor-related protein 2 (HDGFRP2) PWWP domain, dually targets both HDGFRP2 and PSIP1 PWWP domains, engage with the aromatic cage of the HDGFRP2 PWWP domain. |
| PC-22697 |
MUS81 inhibitor 24
MUS81 inhibitor
|
MUS81 inhibitor 24 is a small molecule inhibitor of DNA repair endonuclease Mus81 with IC50 of 0.27 uM and SPR Kd of 1.1 uM (MUS81-EME1). |
| PC-22696 |
MUS81 inhibitor 23
MUS81 inhibitor
|
MUS81 inhibitor 23 is a small molecule inhibitor of DNA repair endonuclease Mus81 with IC50 of 0.32 uM and SPR Kd of 0.67 uM (MUS81-EME1). |
| PC-22445 |
SNM1A inhibitor 19
SNM1A inhibitor
|
SNM1A inhibitor 19 is a cell-active small molecule inhibitor of SNM1A DNA repair nuclease with IC50 of 44 uM, sensitises cancer cells to cisplatin and delays resolution of cisplatin-induced DNA damage. |
| PC-22110 |
GSK_WRN4
WRN helicase inhibitor
|
GSK_WRN4 (WRNi, GSK-WRN4) is a potent and highly selective WRN helicase covalent inhibitor with biochemical pIC50 of 7.6, covalently targets WRN Cys727 residue. |
