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Chemical Structure : RAD51-IN-17
CAS No.: 2101739-18-6
Catalog No.: PC-62839Not For Human Use, Lab Use Only.
RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $98 | In stock | |
| 25 mg | $168 | In stock | |
| 50 mg | $258 | In stock | |
| 100 mg | Get quote |
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RAD51-IN-17 is a quinazolinone derivative that inhibts homologous recombinase RAD51, effectively inhibits both RAD51 foci formation in response to DNA damage, and proliferation of TNBC cell lines.
RAD51-IN-17 also sensitizes aggressive metastatic TNBC to DNA damage induced by irradiation.
RAD51-IN-17 is a valuable research tool for developing combination therapies to overcome RAD51 driven resistance and relapse in a variety of cancers.
| M.Wt | 373.84 | |
| Formula | C22H16ClN3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(E)-3-(4-chlorobenzyl)-2-(2-(pyridin-3-yl)vinyl)quinazolin-4(3H)-one |
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1. Ward A, et al. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3096-3100.
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