| Cat. No. |
Product Name |
Information |
| PC-38504 |
And1 inhibitor CH3
And1 inhibitor
|
And1 inhibitor CH3 is potent acidic nucleoplasmic DNA-binding protein 1 (And-1) inhibitor, reducess And‐1 expression level in IGROV1 cells with IC50 of 2.08 uM. |
| PC-38448 |
PCNA-I1
PCNA inhibitor
|
PCNA-I1 is a small molecule inhibitor of proliferating cell nuclear antigen (PCNA), selectively binds to PCNA trimers with Kd of 0.14-0.41 uM, inhibits the growth of tumor cells of various tissue types with IC50 of 0.2 uM. |
| PC-73255 |
A83B4C63
PNKP inhibitor
|
A83B4C63 is a potent small molecule DNA repair protein, polynucleotide kinase 3′-phosphatase (PNKP) inhibitor with Kd of 80 nM. |
| PC-72920 |
T2AA
PCNA inhibitor
|
T2AA (T2 amino alcohol) is a small molecule proliferating cell nuclear antigen (PCNA) inhibitor, inhibits interaction of PCNA/PIP-box peptide with IC50 of 1 uM. |
| PC-72682 |
BLM inhibitor 2
BLM helicase inhibitor
|
BLM inhibitor 2 is a specific inhibitor of BLM (Bloom syndrome protein) ATPase-coupled DNA helicase activity (IC50=2.2 uM) via the allosteric binding site. |
| PC-72496 |
TH8321
NUDT15 inhibitor
|
TH8321 (TH-8321) is a potent, selective NUDT15 inhibitor with IC50 of 35 nM. |
| PC-72026 |
AZ13792138
NUDT1 inhibitor
|
AZ13792138 is a highly potent, selective inhibitor of MTH1 (NUDT1) with Kd/IC50 of 0.4/0.5 nM. |
| PC-72025 |
SU0383
OGG1-MTH1 inhibitor
|
SU0383 (SU 0383) is a potent, dual inhibitor of repair enzyme OGG1 and NUDT1 (MTH1) with IC50 of 34 nM and 490 nM, respectively. |
| PC-38226 |
TH1760
NUDT15 inhibitor
|
TH1760 (TH 1760) is a first-in-class, potent, selective, cell-active NUDT15 inhibitor with IC50 of 25 nM. |
| PC-35806 |
TH5487
OGG1 inhibitor
|
TH5487 (TH-5487, TH 5487) is a potent, selective, active-site inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 342 nM, prevents OGG1 from binding to its DNA substrate. |
| PC-35301 |
AOH1160
PCNA inhibitor
|
AOH1160 (AOH-1160) is a potent, first-in-class, orally available small molecule inhibitor of Proliferating cell nuclear antigen (PCNA). |
| PC-35266 |
A12B4C3
hPNKP inhibitor
|
A12B4C3 is a potent, specific human polynucleotide kinase/phosphatase (hPNKP) inhibitor, inhibits hPNKP phosphatase activity with IC50 of 60 nM. |
