Chemical Structure : H3B-960
CAS No.: 2912294-89-2
Catalog No.: PC-21005Not For Human Use, Lab Use Only.
H3B-960 is a potent, selective and covalent inhibitor of Werner syndrome protein (WRN) helicase activity with IC50 of 60 nM.
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H3B-960 is a potent, selective and covalent inhibitor of Werner syndrome protein (WRN) helicase activity with IC50 of 60 nM.
M.Wt | 534.43 | |
Formula | C21H16F6N4O4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-(p-tolyl)-2-((4-(4-(trifluoromethoxy)phenyl)-6-(trifluoromethyl)pyrimidine)-2-sulfonamido)acetamide |
1. Mackenzie J Parker, et al. Biochemistry. 2023 Jul 18;62(14):2147-2160.
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