H3B-960 | WRN helicase inhibitor | Probechem Biochemicals

Chemical Structure : H3B-960

CAS No.: 2912294-89-2

Catalog No.: PC-21005Not For Human Use, Lab Use Only.

H3B-960 is a potent, selective and covalent inhibitor of Werner syndrome protein (WRN) helicase activity with IC50 of 60 nM.

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Biological Activity

H3B-960 is a potent, selective and covalent inhibitor of Werner syndrome protein (WRN) helicase activity with IC50 of 60 nM.

M.Wt	534.43
Formula	C21H16F6N4O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(p-tolyl)-2-((4-(4-(trifluoromethoxy)phenyl)-6-(trifluoromethyl)pyrimidine)-2-sulfonamido)acetamide

1. Mackenzie J Parker, et al. Biochemistry. 2023 Jul 18;62(14):2147-2160.