GSK_WRN2 | WRN helicase inhibitor | Probechem Biochemicals

Chemical Structure : GSK_WRN2

GSK_WRN2 (GSK-WRN2)

Catalog No.: PC-22108Not For Human Use, Lab Use Only.

GSK_WRN2 (GSK-WRN2) is a potent and highly selective WRN helicase covalent inhibitor with biochemical pIC50 of 6.5, covalently targets WRN Cys727 residue.

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Biological Activity

GSK_WRN2 (GSK-WRN2) is a potent and highly selective WRN helicase covalent inhibitor with biochemical pIC50 of 6.5, covalently targets WRN Cys727 residue.

Physicochemical Properties

M.Wt	309.33
Formula	C17H15N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(methylamino)-4-oxobut-2-yn-1-yl)-2-oxo-6-phenyl-1,2-dihydropyridine-3-carboxamide

References

1. Picco G, et al. Cancer Discov. 2024 Apr 9. doi: 10.1158/2159-8290.CD-24-0052.

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GSK_WRN2 (GSK-WRN2)

Biological Activity

Physicochemical Properties

References

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