H3B-968 | WRN helicase inhibitor | Probechem Biochemicals

Chemical Structure : H3B-968

CAS No.: 2912294-90-5

H3B-968 (H3B 968)

Catalog No.: PC-21006Not For Human Use, Lab Use Only.

H3B-968 is a potent, selective and covalent inhibitor of Werner syndrome protein (WRN) helicase activity with IC50 of 41 and 13 nM in ADP-Glo assay DNA unwinding assay, respectively.

Packing	Price	Stock
5 mg	$278	In stock
10 mg	$458	In stock
25 mg	$758	In stock
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

H3B-968 is a potent, selective and covalent inhibitor of Werner syndrome protein (WRN) helicase activity with IC50 of 41 and 13 nM in ADP-Glo assay DNA unwinding assay, respectively.

Physicochemical Properties

M.Wt	548.46
Formula	C22H18F6N4O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-ethylphenyl)-2-((4-(4-(trifluoromethoxy)phenyl)-6-(trifluoromethyl)pyrimidine)-2-sulfonamido)acetamide

References

1. Mackenzie J Parker, et al. Biochemistry. 2023 Jul 18;62(14):2147-2160.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

H3B-968 (H3B 968)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.