Werner syndrome RecQ helicase-IN-2

Chemical Structure : Werner syndrome RecQ helicase-IN-2

CAS No.: 2869954-51-6

Catalog No.: PC-20675Not For Human Use, Lab Use Only.

Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor with IC50 of 100 nM for WRN ATPase.

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Biological Activity

Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor with IC50 of 100 nM for WRN ATPase.

M.Wt	681.68
Formula	C32H34F3N9O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-(4-(5-hydroxy-6-methylpyrimidine-4-carbonyl)piperazin-1-yl)-7-oxo-[1,2,4]triazolo[1,5-a]pyrimidin-4(7H)-yl)-N-(2-methyl-4-(trifluoromethyl)phenyl)acetamide

1. Patent WO2022249060 (Example 57).