Chemical Structure : Werner syndrome RecQ helicase-IN-2
CAS No.: 2869954-51-6
Catalog No.: PC-20675Not For Human Use, Lab Use Only.
Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor with IC50 of 100 nM for WRN ATPase.
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Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor with IC50 of 100 nM for WRN ATPase.
M.Wt | 681.68 | |
Formula | C32H34F3N9O5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-(2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-(4-(5-hydroxy-6-methylpyrimidine-4-carbonyl)piperazin-1-yl)-7-oxo-[1,2,4]triazolo[1,5-a]pyrimidin-4(7H)-yl)-N-(2-methyl-4-(trifluoromethyl)phenyl)acetamide |
1. Patent WO2022249060 (Example 57).
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