Chemical Structure : Werner syndrome RecQ helicase-IN-3
CAS No.: 2869954-98-1
Catalog No.: PC-20676Not For Human Use, Lab Use Only.
Werner syndrome RecQ helicase-IN-3 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor with IC50 of 60 nM for WRN ATPase.
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Werner syndrome RecQ helicase-IN-3 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor with IC50 of 60 nM for WRN ATPase.
M.Wt | 687.07 | |
Formula | C31H30ClF3N8O5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-(2-chloro-4-(trifluoromethyl)phenyl)-2-(2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-(4-(3-hydroxypicolinoyl)piperazin-1-yl)-7-oxo-[1,2,4]triazolo[1,5-a]pyrimidin-4(7H)-yl)acetamide |
1. Patent WO2022249060A1.
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