HUHS-015 |CAS:1453097-13-6 Probechem Biochemicals

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Chemical Structure : HUHS-015

CAS No.: 1453097-13-6

HUHS-015 (HUHS015)

Catalog No.: PC-42079Not For Human Use, Lab Use Only.

HUHS-015 (HUHS015) is a potent, orally active prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitor with IC50 of 0.67 uM.

Packing	Price	Stock
25 mg	$128	In stock
50 mg	$198	In stock
100 mg	$348	In stock
500 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

HUHS-015 (HUHS015) is a potent, orally active prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitor with IC50 of 0.67 uM.
HUHS-015 significantly suppresses the growth of DU145 cells in vitro and in a mouse xenograft model.

Physicochemical Properties

M.Wt	318.3724
Formula	C19H18N4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 34 mg/mL
Chemical Name/SMILES	1H-Pyrazol-5-ol, 3-methyl-1-(6-methyl-1H-benzimidazol-2-yl)-4-(phenylmethyl)-

References

1. Nakao S, et al. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1071-4.

2. Mabuchi M, et al. In Vivo. 2015 Jan-Feb;29(1):39-43.

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HUHS-015 (HUHS015)

Biological Activity

Physicochemical Properties

References

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