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SAR-24

Chemical Structure : SAR-24

CAS No.: 1321755-68-3

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SAR-24 (PCNA-I1S, SAR24)

Catalog No.: PC-24067Not For Human Use, Lab Use Only.

SAR-24 (PCNA-I1S) is a small molecule inhibitor of proliferating cell nuclear antigen (PCNA), significantly affects chromatin-associated PCNA in tumor cells, effectively decreasing its levels and thereby inhibiting cancer cell proliferation.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SAR-24 (PCNA-I1S) is a small molecule inhibitor of proliferating cell nuclear antigen (PCNA), significantly affects chromatin-associated PCNA in tumor cells, effectively decreasing its levels and thereby inhibiting cancer cell proliferation.

    Physicochemical Properties

    M.Wt 306.32
    Formula C18H14N2O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (Z)-2-hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide

    References

    1. Dillehay KL, et al. Pharmacol Res Perspect. 2015 Mar;3(2):e00115.

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