Chemical Structure : Calicheamicin
CAS No.: 108212-75-5
Catalog No.: PC-45655Not For Human Use, Lab Use Only.
Calicheamicin (Calicheamicin γ1) is an enediyne antitumor antibiotic that acts by binding to DNA and causes strand scission, an ADC payload used in development of antibody drug conjugates.
Bulk size, bulk discount!
Welcome credit card payment!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Calicheamicin (Calicheamicin γ1) is an enediyne antitumor antibiotic that acts by binding to DNA and causes strand scission, an ADC payload used in development of antibody drug conjugates.
M.Wt | 1368.348 | |
Formula | C55H74IN3O21S4 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
Carbamic acid, N-[(1R,4Z,8S,13E)-8-[[4,6-dideoxy-4-[[[2,6-dideoxy-4-S-[4-[(6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-3-iodo-5,6-dimethoxy-2-methylbenzoyl]-4-thio-β-D-ribo-hexopyranosyl]oxy]amino]-2-O-[2,4-dideoxy-4-(ethylamino)-3-O-methyl-α-L-threo-pento |
1. Lambert JM, et al. Adv Ther. 2017 May;34(5):1015-1035.
2. Guffroy M, et al. Clin Cancer Res. 2017 Apr 1;23(7):1760-1770.
3. Damelin M, et al. Clin Cancer Res. 2015 Sep 15;21(18):4165-73.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright