| Cat. No. |
Product Name |
Information |
| PC-35367 |
SG3199
ADC payload
|
SG3199 (SG-3199) is a PBD dimer warhead component of antibody-drug conjugate (ADC) payload tesirine, demonstrates potently cytotoxic against a panel of human solid tumour and haematological cancer cell lines with mean GI50 of 151.5 pM. |
| PC-43366 |
Daunorubicin hydrochloride
Topo II inhibitor
|
Daunorubicin (RP13057) hydrochloride is potent topoisomerase II (Topo II) inhibitor, interacts with DNA by intercalation and inhibition of macromolecular biosynthesis in cancer cells. |
| PC-60141 |
SGD-1882
|
PBD dimer;Pyrrolobenzodiazepine dimer novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs). |
| PC-60140 |
D211
|
A novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs). |
| PC-45714 |
Mertansine
|
Mertansine (DM1) is a tubulin inhibitor. |
| PC-21891 |
ZD06519
ADC payload
|
ZD06519 is a novel camptothecin payload for antibody drug conjugates (ADCs) with highp ayload potency (~1 nM). |
| PC-43367 |
Daunorubicin
|
Daunorubicin is potent topoisomerase II (Topo II) inhibitor, interacts with DNA by intercalation and inhibition of macromolecular biosynthesis in cancer cells. |
| PC-43365 |
Daun02
|
Daun02 a prodrug that is converted by β-galactosidase to Daunorubicin, inactivate activated neurons that express both β-galactosidase and Fos, specifically attenuates cocaine-induced locomotor activity, also attenuates cocaine-induced β-galactosidase expression. |
| PC-70085 |
Esperamicin A1
|
Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin. |
| PC-45656 |
alpha-Amanitin
|
α-Amanitin, an 8-Aa cyclic peptide, is an selective inhibitor of RNA polymerase II and III. |
| PC-45636 |
Maytansinol
|
Maytansinol (Ansamitocin P-0) is a microtubule assembly inhibitor. |
| PC-45655 |
Calicheamicin
|
Calicheamicin γ1 is an enediyne antitumor antibiotic that acts by binding to DNA and causes strand scission. |
