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ZD06519

Chemical Structure : ZD06519

CAS No.: 2873460-17-2

ZD06519 (ZD 06519)

Catalog No.: PC-21891Not For Human Use, Lab Use Only.

ZD06519 is a novel camptothecin payload for antibody drug conjugates (ADCs) with highp ayload potency (~1 nM).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ZD06519 is a novel camptothecin payload for antibody drug conjugates (ADCs) with highp ayload potency (~1 nM).

Physicochemical Properties

M.Wt 497.48
Formula C25H24FN3O7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-hydroxyethyl (S)-((4-ethyl-8-fluoro-4-hydroxy-9-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-11-yl)methyl)carbamate

References

1. Mark E Petersen, et al. Mol Cancer Ther. 2024 Feb 14. doi: 10.1158/1535-7163.MCT-23-0822.

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