SGD-1882 |CAS:1222490-34-7 Probechem Biochemicals

Chemical Structure : SGD-1882

SGD-1882 (PBD dimer;Pyrrolobenzodiazepine dimer)

Catalog No.: PC-60141Not For Human Use, Lab Use Only.

PBD dimer;Pyrrolobenzodiazepine dimer novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs).

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Biological Activity

SGD-1882 (PBD dimer, Pyrrolobenzodiazepine dimer) is a novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs).

Physicochemical Properties

M.Wt	725.802
Formula	C42H39N5O7
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(4-aminophenyl)-7-methoxy-8-(3-(((S)-7-methoxy-2-(4-methoxyphenyl)-5-oxo-5,11a-dihydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-8-yl)oxy)propoxy)-1,11a-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one

References

1. Sean W. Smith, et al. ACS Med. Chem. Lett. DOI: 10.1021/acsmedchemlett.7b00436

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SGD-1882 (PBD dimer;Pyrrolobenzodiazepine dimer)

Biological Activity

Physicochemical Properties

References

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