alpha-Amanitin |CAS:23109-05-9 Probechem Biochemicals

Chemical Structure : alpha-Amanitin

CAS No.: 23109-05-9

alpha-Amanitin (α-Amanitin;α-Amatoxin)

Catalog No.: PC-45656Not For Human Use, Lab Use Only.

α-Amanitin, an 8-Aa cyclic peptide, is an selective inhibitor of RNA polymerase II and III.

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Biological Activity

α-Amanitin, an 8-Aa cyclic peptide, is an selective inhibitor of RNA polymerase II and III; a suitable toxic ADC payload for antibody-drug conjugates design.

Physicochemical Properties

M.Wt	918.9697
Formula	C39H54N10O14S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	α-Amanitin

References

1. Davis MT, et al. Science. 1981 Sep 18;213(4514):1385-8.

2. Kume K, et al. Sci Rep. 2016 May 16;6:25895.

3. Wagner SD, et al. EMBO J. 2013 Mar 20;32(6):781-90.

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alpha-Amanitin (α-Amanitin;α-Amatoxin)

Biological Activity

Physicochemical Properties

References

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