IRAK3 PROTAC 23

Chemical Structure : IRAK3 PROTAC 23

Catalog No.: PC-72479Not For Human Use, Lab Use Only.

IRAK3 PROTAC 23 a potent and selective degrader of IRAK3 with DC50 of 2 nM, with a maximum degradation measured of 98%.

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Biological Activity

IRAK3 PROTAC 23 a potent and selective degrader of IRAK3 with DC50 of 2 nM, with a maximum degradation measured of 98%.

M.Wt	878.092
Formula	C47H63N11O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2,6-Dioxo-3-piperidyl)-5-[4-[2-[1-[4-[4-[cis-4-[(5-isopropylpyrrolo[2,1-f][1,2,4]triazin-4- yl)amino]cyclohexyl]piperazin-1-yl]-4-oxo-butanoyl]-4-piperidyl]ethyl]piperazin-1- yl]isoindoline-1,3-dione

1. Sébastien L Degorce, et al. J Med Chem. 2020 Sep 24;63(18):10460-10473.