Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-ADCs and PROTACs-PROTAC

Request The Product List ofPROTAC PROTAC

Cat. No. Product Name Information
PC-25158

FAK PROTAC D4

FAK degrader

FAK PROTAC D4 is a potent and highly selective FAK PROTAC degrader with DC50 of 1.08 nM in PA-1 cells.
PC-25153

AURKB PROTAC MS44

Aurora kinase B PROTAC

AURKB PROTAC MS44 is a potent, selective, first-in-class Aurora B kinase (AURKB) PROTAC degrader with DC50 of 103 nM in HPAF-11 cells, Dmax of 89%.
PC-24992

JMV7048

PXR PROTAC

JMV7048 is a potent, selective and effective PROTAC degrader of pregnane X receptor (PXR) with DC50 of 379 nM.
PC-24991

MI1013

PXR PROTAC

MI1013 is a potent, selective CRBN-base PROTAC degrader of pregnane X receptor (PXR) designed by connecting SPA70 and pomalidomide with PEG linker, has DC50 of 89 nM and Dmax of 82% in HepaRG cells.
PC-24975

SD-91

STAT3 PROTAC

SD-91 is a potent, selective STAT3 PROTAC degrader with DC50 of 17 nM in SU-DHL-1 cell line.
PC-24938

NK7-902

NEK7 degrader

NK7-902 is a potent and selective cereblon (CRBN) glue degrader of NEK7 with DC50 of 0.2 nM in human primary monocytes (Dmax>95%).
PC-24930

YT-58

BTK PROTAC

YT-58 is a selective, RBBP7-recruiting BTK PROTAC degrader with DC50 of 0.17 uM (Dmax=83%), induces BTK degradation via the proteasome pathway and effectively inhibits BTK and PLCγ2 phosphorylation.
PC-24916

PRMT4 PROTAC C199

PRMT4 degrader

PRMT4 PROTAC C199 is a potent, selective PROTAC degrader targeting PRMT4 with DC50 of 106 nM and Dmax=93.1% in NCI-H929 cells, showes high selectivity for PRMT4 over other PRMTs.
PC-24903

SJ46420

BRD3 PROTAC

SJ46420 is the a methyl-ester prodrug of SJ46421 and specific JQ1-based KLHDC2 PROTAC protein degrader of BRD3, induces selective BRD3 degradation in PC3 cells with DC50 of 487 nM (Dmax=99%).
PC-24902

SJ46421

BRD3 PROTAC

SJ46421 is a specific JQ1-based KLHDC2 PROTAC protein degrader of BRD3, induces selective BRD3 degradation in cells, promotes selective cooperative ternary complex formation with BRD3BD2 with IC50 of 7.8 nM.
PC-24888

INY-05-040

AKT PROTAC

INY-05-040 is a second-generation pan-AKT PROTAC degrader, selectively and rapidly (<5 h) degrades all three AKT isoforms and inhibits downstream signaling and cell proliferation in 288 cancer cell lines.
PC-24880

dASK1-VHL

ASK1 PROTAC

dASK1-VHL is a potent, selective cereblon (CRBN)-based PROTAC degrader of apoptosis signal-regulating kinase 1 (ASK1).

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com