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YZ268

Chemical Structure : YZ268

CAS No.:

YZ268 (YZ-268, HDAC6 Degrader 13f)

Catalog No.: PC-72092Not For Human Use, Lab Use Only.

HDAC6 Degrader 13f (YZ268) is a selective HDAC6 degrader (PROTAC) with high potency, specific chemical probe to knock-down HDAC6.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    HDAC6 Degrader 13f (YZ268) is a selective HDAC6 degrader (PROTAC) with high potency, specific chemical probe to knock-down HDAC6.

    Physicochemical Properties

    M.Wt 884.05
    Formula C49H57N9O7
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Month
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-((1-butyl-3-(4-((7-(4-(((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)benzyl)amino)methyl)-1H-1,2,3-triazol-1-yl)heptyl)oxy)phenyl)ureido)methyl)-N-hydroxybenzamide

    References

    1. Ka Yang, et al. Cell Chem Biol. 2020 Jul 16;27(7):866-876.e8.

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