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Sovutrecdeg

Chemical Structure : Sovutrecdeg

CAS No.: 2412058-69-4

Sovutrecdeg (CG001419, CG-001419)

Catalog No.: PC-27503Not For Human Use, Lab Use Only.

Sovutrecdeg (CG001419) is a first-in-class, selective, potent oral degrader of pan-tropomyosin receptor kinase (TRK), selectively degrades both mutant and wild-type TRK proteins.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Sovutrecdeg (CG001419) is a first-in-class, selective, potent oral degrader of pan-tropomyosin receptor kinase (TRK), selectively degrades both mutant and wild-type TRK proteins.

    Physicochemical Properties

    M.Wt 871.95
    Formula C47H47F2N9O6
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    Benzamide, N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-[4-[[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]methyl]-1-piperazinyl]-2-[(tetrahydro-2H-pyran-4-yl)amino]-

    References

    1. Patent WO2021170109 A1 2021-09-02.

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