| Cat. No. |
Product Name |
Information |
| PC-20515 |
Sparsentan
Dual AT-II and ETA antagonist
|
Sparsentan (RE-021, DARA-a) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Ki values of 0.8 and 9.3 nM, respectively. |
| PC-49657 |
Forasartan
AT1 receptor inhibitor
|
Forasartan (SC-52458) is a potent, specific, competitive and reversible angiotensin II receptor (AT1 receptor) antagonist with binding Ki value of 2.9 nM. |
| PC-73402 |
Azilsartan mopivabil
AT2R antagonist
|
Azilsartan mopivabil is a potent, selective angiotensin II receptor (AT2R) antagonist, with potential for hypertension, chronic heart failure and diabetic nephropathy. |
| PC-73401 |
Azilsartan mepixetil
AT2R antagonist
|
Azilsartan mepixetil is a potent, selective angiotensin II receptor antagonist, with potential for hypertension, chronic heart failure and diabetic nephropathy. |
| PC-72732 |
DCP1-3
AT1R allosteric modulator
|
DCP1-3 is a novel allosteric ligand of the angiotensin receptor AT1R, displays NAM potency on AngIV with IC50 of 0.29 uM. |
| PC-35877 |
TD-0212
AT1/Neprilysin (NEP) inhibitor
|
TD-0212 (TD0212) is a potent, orally efficacious, dual AT1 antagonist/Neprilysin (NEP) inhibitor with pKi of 8.9 (AT1) and pIC50 of 9.2 (NEP). |
| PC-43383 |
EMA401
AT2R inhibitor
|
EMA401 (Olodanrigan) is a potent, highly selective angiotensin II type 2 receptor (AT2R) antagonist, inhibits capsaicin responses in cultured neurons of human and rat DRG with IC50 of 10 nM. |
| PC-43020 |
CGP-42112
AT2 receptor agonist
|
CGP-42112 (CGP42112A) is a highly potent, selective Angiotensin-II subtype 2 receptor(AT2 receptor) agonist with Ki of 0.24 nM. |
| PC-43019 |
Angiotensin 1-7
|
Angiotensin (1-7) (Ang-(1-7)) is an active heptapeptide of the Renin-angiotensin system (RAS), inhibits purified canine angiotensin converting enzyme (ACE) activity with IC50 of 0.65 uM. |
| PC-62642 |
EMA300
AT2 receptor antagonist
|
EMA300 (PD121981) is a potent, selective small molecule antagonist of angiotensin II type 2 receptor (AT2R) with >1,000-fold selectivity over AT1 receptor. |
| PC-45692 |
BIBS-39
Angiotensin receptor antagonist
|
BIBS-39 (BIBS 39) is a selective nonpeptide angiotensin II receptor antagonist with Ki of 29 nM and 480 nM for AT1 and AT2 respectively. |
| PC-44124 |
Azilsartan
AT1 inhibitor
|
Azilsartan (TAK-536) is a specific and potent angiotensin II type 1 receptor (AT1) antagonist with IC50 of 2.6 nM, used in the treatment of adults with essential hypertension. |
