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Telmisartan

Chemical Structure : Telmisartan

CAS No.: 144701-48-4

Telmisartan (BIBR-277, BIBR277)

Catalog No.: PC-24210Not For Human Use, Lab Use Only.

Telmisartan (BIBR-277) is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), inhibits binding of 125I-AngII to AT1 receptor with IC50 of 9.2 nM.

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Biological Activity

Telmisartan (BIBR-277) is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), inhibits binding of 125I-AngII to AT1 receptor with IC50 of 9.2 nM.

Physicochemical Properties

M.Wt 514.63
Formula C33H30N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid

References

1. Maillard MP, et al. J Pharmacol Exp Ther. 2002 Sep;302(3):1089-95.

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