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Azilsartan medoxomil

Chemical Structure : Azilsartan medoxomil

CAS No.: 863031-21-4

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Azilsartan medoxomil (TAK 491;TAK-491;TAK491)

Catalog No.: PC-44046Not For Human Use, Lab Use Only.

A specific and potent angiotensin II type 1 receptor (AT1) antagonist with IC50 of 2.6 nM, used in the treatment of adults with essential hypertension. .

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A specific and potent angiotensin II type 1 receptor (AT1) antagonist with IC50 of 2.6 nM, used in the treatment of adults with essential hypertension.

Hypertension

Approved

Physicochemical Properties

M.Wt 568.5336
Formula C30H24N4O8
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1H-Benzimidazole-7-carboxylic acid, 1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester

References

1. French C, et al. J Cardiovasc Pharmacol. 2011 Aug;58(2):143-8.

2. Kusumoto K, et al. Eur J Pharmacol. 2011 Nov 1;669(1-3):84-93.

3. Bönner G, et al. J Hum Hypertens. 2013 Aug;27(8):479-86.

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