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Chemical Structure : CGP-42112
CAS No.: 127060-75-7
Catalog No.: PC-43020Not For Human Use, Lab Use Only.
CGP-42112 (CGP42112A) is a highly potent, selective Angiotensin-II subtype 2 receptor(AT2 receptor) agonist with Ki of 0.24 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $128 | In stock | |
| 5 mg | $358 | In stock | |
| 25 mg | Get quote |
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CGP-42112 (CGP42112A) is a highly potent, selective Angiotensin-II subtype 2 receptor(AT2 receptor) agonist with Ki of 0.24 nM; significantly inhibits cGMP production from the basal value, also significantly inhibits TH-enzyme activity from the basal value in cultured porcine adrenal medullary cells; antagonizes Ang-II induced contractions in rabbit aortic rings with IC50 of 1.85 uM.
| M.Wt | 1052.185 | |
| Formula | C52H69N13O11 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 350 mg/mL |
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| Chemical Name/SMILES |
L-Isoleucine, N-(3-pyridinylcarbonyl)-L-tyrosyl-N6-[N2-[(phenylmethoxy)carbonyl]-L-arginyl]-L-lysyl-L-histidyl-L-prolyl- |
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1. Hakam AC, et al. Am J Physiol Renal Physiol. 2006 Jun;290(6):F1430-6.
2. Takekoshi K, et al. Biochem Biophys Res Commun. 2000 Jun 7;272(2):544-50.
3. Näveri L, et al. J Cereb Blood Flow Metab. 1994 Jan;14(1):38-44.
4. Näveri L, et al. Acta Physiol Scand Suppl. 1995;630:1-48.
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