EMA300 |CAS:136676-76-1 Probechem Biochemicals

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Chemical Structure : EMA300

EMA300 (PD121981)

Catalog No.: PC-62642Not For Human Use, Lab Use Only.

EMA300 (PD1 21981) is a potent, selective small molecule antagonist of angiotensin II type 2 receptor (AT2R) with >1,000-fold selectivity over AT1 receptor, produces analgesia in rodent model of neuropathic pain..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	495.579
Formula	C30H29N3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Imidazo[4,5-c]pyridine-6-carboxylic acid, 5-(diphenylacetyl)-4,5,6,7-tetrahydro-1-[(4-methoxy-3-methylphenyl)methyl]-, (S)- (9CI)

References

1. Smith MT, et al. Pain Med. 2013 Oct;14(10):1557-68.

2. Smith MT, et al. Behav Pharmacol. 2014 Apr;25(2):137-46.

3. Khan N, et al. Front Mol Neurosci. 2017 Nov 21;10:389.

4. Smith MT, et al. Pain Med. 2013 May;14(5):692-705.

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EMA300 (PD121981)

Biological Activity

Physicochemical Properties

References

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