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Cat. No. Product Name Information
PC-49713

SW120619

WNK3 inhibitor

SW120619 is a specific small molecule inhibitor of WNK3 kinase with IC50 of 0.7 uM, weakly inhibits WNK1 and WNK2 with IC50 of 2.3 and 16.8 uM, respectively.
PC-49712

SW118150

WNK3 inhibitor

SW118150 is a selective small molecule inhibitor of WNK3 kinase with IC50 of 3.0 uM, 5-fold selectivity over WNK1.
PC-61065

WNK inhibitor 7

WNK1 inhibitor

WNK inhibitor 7 (WNK-IN-7) is a potent, selectiive inhibitor of WNK1 kinase with IC50 of 95 nM, shows IC50 of 1.39 uM in the cellular OSR1 phosphorylation assay with reasonable aqueous solubility.
PC-61064

WNK inhibitor 11

WNK inhibitor

WNK inhibitor 11 is a potent, selectiive and orally active inhibitor of WNK1 kinase with IC50 of 6 nM, 1,000-fold selectivity over WNK4 and 57-fold selectivity over WNK2.
PC-42214

WNK463

WNK inhibitor

WNK463 is the first, potent, selective, and orally bioavailable pan With-No-Lysine (WNK) Kinase catalytic activity inhibitor with IC50 of 5/1/6/9 nM for WNK1/2/3/4, respectively.

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