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SW120619

Chemical Structure : SW120619

CAS No.: 2702273-17-2

SW120619 (SW 120619)

Catalog No.: PC-49713Not For Human Use, Lab Use Only.

SW120619 is a specific small molecule inhibitor of WNK3 kinase with IC50 of 0.7 uM, weakly inhibits WNK1 and WNK2 with IC50 of 2.3 and 16.8 uM, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SW120619 is a specific small molecule inhibitor of WNK3 kinase with IC50 of 0.7 uM, weakly inhibits WNK1 and WNK2 with IC50 of 2.3 and 16.8 uM, respectively.

Physicochemical Properties

M.Wt 378.47
Formula C19H14N4OS2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-isothiocyanatoethyl)-6-(naphthalen-2-yl)imidazo[2,1-b]thiazole-5-carboxamide

References

1. Chlebowicz J, et al. Drug Des Devel Ther. 2023 Jan 20;17:93-105.

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