Chemical Structure : INF200
Catalog No.: PC-22764Not For Human Use, Lab Use Only.
INF200 is a novel sulfonylurea-based NLRP3 inhibitor, specifically inhibits NLRP3-driven pyroptosis with IC50 of 1.55 uM, efficiently reduces cardiac and metabolic complications in in vivo model of diet-induced metaflammation.
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INF200 is a novel sulfonylurea-based NLRP3 inhibitor, specifically inhibits NLRP3-driven pyroptosis with IC50 of 1.55 uM, efficiently reduces cardiac and metabolic complications in in vivo model of diet-induced metaflammation. IFN200 reduced IRI-dependent NLRP3 activation, inflammation, and oxidative stress.
| M.Wt | 296.71 | |
| Formula | C13H13ClN2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Simone Gastaldi, et al. Eur J Med Chem. 2023 Sep 5:257:115542.

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