INF200 | NLRP3 inhibitor | Probechem Biochemicals

Chemical Structure : INF200

INF200 (INF 200, INF-200)

Catalog No.: PC-22764Not For Human Use, Lab Use Only.

INF200 is a novel sulfonylurea-based NLRP3 inhibitor, specifically inhibits NLRP3-driven pyroptosis with IC50 of 1.55 uM, efficiently reduces cardiac and metabolic complications in in vivo model of diet-induced metaflammation.

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Biological Activity

Physicochemical Properties

M.Wt	296.71
Formula	C13H13ClN2O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl 2-(5-(2-chlorobenzyl)-2-oxo-1,3,4-oxadiazol-3(2H)-yl)acetate

References

1. Simone Gastaldi, et al. Eur J Med Chem. 2023 Sep 5:257:115542.

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INF200 (INF 200, INF-200)

Biological Activity

Physicochemical Properties

References

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