CP-466722 |CAS:1080622-86-1 Probechem Biochemicals

Chemical Structure : CP-466722

CAS No.: 1080622-86-1

CP-466722 (CP466722;CP 466722)

Catalog No.: PC-42778Not For Human Use, Lab Use Only.

CP-466722 is a poten and selective ATM inhibitor (IC50=0.41 uM) without effect on ATR kinase, does not inhibit PI3K, PI3K-like protein kinases or Abl kinase.

Packing	Price	Stock
5 mg	$78	In stock
10 mg	$118	In stock
25 mg	$188	In stock
50 mg	$298	In stock
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Biological Activity

CP-466722 is a poten and selective ATM inhibitor (IC50=0.41 uM) without effect on ATR kinase, does not inhibit PI3K, PI3K-like protein kinases or Abl kinase.
CP-466722 disrupts ATM-dependent cell cycle checkpoints in cells.

Physicochemical Properties

M.Wt	349.3467
Formula	C17H15N7O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: 7 mg/mL (Need warming)
Chemical Name/SMILES	1H-1,2,4-Triazol-5-amine, 1-(6,7-dimethoxy-4-quinazolinyl)-3-(2-pyridinyl)-

References

1. Rainey MD, et al. Cancer Res. 2008 Sep 15;68(18):7466-74.

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CP-466722 (CP466722;CP 466722)

Biological Activity

Physicochemical Properties

References

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