Chemical Structure : Ovatodiolide
CAS No.: 3484-37-5
Catalog No.: PC-28346Not For Human Use, Lab Use Only.
Ovatodiolide is a diterpenoid from a Chinese herb that possesses anticancer, anti-bacterial and anti-inflammatory properties, induces cell cycle G2/M arrest and apoptosis via a ROS-dependent ATM/ATR signaling in lung cancer cells.
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|---|---|---|---|
| 1 mg | $138 | In stock | |
| 5 mg | $328 | In stock | |
| 10 mg | $258 | In stock | |
| 25 mg | Get quote |
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Ovatodiolide is a diterpenoid from a Chinese herb that possesses anticancer, anti-bacterial and anti-inflammatory properties, induces cell cycle G2/M arrest and apoptosis via a ROS-dependent ATM/ATR signaling in lung cancer cells.
Ovatodiolide induces cell cycle arrest and apoptosis in human oral squamous cell carcinoma Ca9-22 cells.
Ovatodiolide possesses bactericidal activity against H. pylori by reducing levels of ribosomal protein RpsB.
Ovatodiolide induces cell cycle G2/M arrest and apoptosis via a ROS-dependent ATM/ATR signaling pathways in lung cancer A549 and H1299 cells.
Ovatodiolide suppresses allergic airway inflammation and hyperresponsiveness in a murine model of asthma.
Ovatodiolide inhibits SARS-CoV-2 replication and ameliorates pulmonary fibrosis through suppression of the TGF-beta/TbetaRs signaling pathway.
| M.Wt | 328.41 | |
| Formula | C20H24O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
O=C(O1)C([C@@](CC/C(C)=C/CCC2=C3)([H])[C@@]1([H])/C=C(C)/C[C@]3([H])OC2=O)=C |
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1. Arisawa M, et al. Planta Med. 1986 Aug;(4):297-9.
2. Hou YY, et al. Life Sci. 2009 Jul 3;85(1-2):26-32.
3. Lien HM, et al. Sci Rep. 2019 Mar 12;9(1):4205.
4. Yu CY, et al. Eur J Pharmacol. 2018 Jan 15;819:16-29.

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