Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Cell Cycle/DNA Damage-ATM/ATR

Request The Product List ofATM/ATR ATM/ATR

Cat. No. Product Name Information
PC-22828

AD1058

ATR inhibitor

AD1058 is a highly potent, selective, brain-penetrant ATR inhibitor with IC50 of 1.6 nM.
PC-22113

XRD-0394

ATM/DNA-PK inhibitor

XRD-0394 (XRD0394) is a potent and specific dual inhibitor of DNA damage-response kinases ATM and DNA-PK with IC50 of 0.39 and 0.89 nM respectively.
PC-21873

ART0380

ATR inhibitor

Alnodesertib (ART0380, ART-0380) is a potent, selective and ATP-competitive ATR kinase inhibitor, inhibits ATR-ATRIP complex enzyme activity with IC50 of 51.7 nM, and phospho-Chk1 IC50 of 22 nM in cell western assay.
PC-21522

CGK733

ATM/ATR inhibitor

CGK733 is a specific small molecule inhibitor of ATM and ATR kinases, induces cell death in prematurely senescent breast cancer cells.
PC-73375

M3541

ATM inhibitor

M3541 (M 3541) is a novel potent, selective and ATP-competitive ATM kinase inhibitor with IC50 of 0.25 nM (ATP, 10 uM).
PC-72900

M4076

ATM inhibitor

Lartesertib (M4076) is a higly potent, selective, ATP-competitive inhibitor of ATM kinase with IC50 of 0.2 nM.
PC-72744

SKLB-197

ATR inhibitor

SKLB-197 is a potent and highly selective ATR kinase inhibitor with IC50 of 13 nM.
PC-72315

RP-3500

ATR inhibitor

RP-3500 (RP3500, Camonsertib) is a novel potent, selective, orally bioavailable ATR inhibitor with IC50 of 1.0 and 0.33 nM in biochemical and cell-based assays, respectively.
PC-72164

Berzosertib

ATR inhibitor

Berzosertib (M6620, VX-970, VE-822) is a highly potent, selective ATR inhibitor with Ki of 0.17 nM, pH2AX IC50 of 19 nM.
PC-72163

M4344

ATR inhibitor

M4344 (VX-803, Gartisertib) is a highly potent, selective ATR inhibitor with Ki<0.15 nM.
PC-35077

AZ32

ATM inhibitor

AZ32 (ATM inhibitor AZ32) is a potent, selective, orally bioavailable, BBB-penetrating ATM inhibitor with IC50 of <6.2 nM, effectively blocks ATM auto-phosphorylation at S1981 with IC50 of 0.31 uM.
PC-42876

KU-60019

ATM inhibitor

KU-60019 (KU60019) is an improved analogue of KU-55933, and is a potent, specific inhibitor of ATM kinase with IC50 of 6.3 nM, 270- and 1,600-fold selectivity over DNA-PKcs and ATR.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com