| Cat. No. |
Product Name |
Information |
| PC-49742 |
NS3694
Caspase inhibitor
|
NS3694 (NS 3694) is a specific cell-permeable diarylurea compound that inhibits apoptosome formation and caspase activation, blocks cytochrome c-induced caspase activation in HeLa cell cytosolic extracts with IC50 of 50 uM. |
| PC-73051 |
Procaspase-6 inhibitor 13
Procaspase-6 inhibitor
|
Procaspase-6 inhibitor 13 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.38 uM. |
| PC-73050 |
Procaspase-6 inhibitor 12
Procaspase-6 inhibitor
|
Procaspase-6 inhibitor 12 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.47 uM. |
| PC-73049 |
PG3d
Caspase-6 inhibitor
|
PG3d (Caspase-6 inhibitor PG3d) is a cell-active, allosteric and irreversible, non-competitive Caspase-6 inhibitor. |
| PC-72960 |
NH-23-C2
Caspase-2 inhibitor
|
NH-23-C2 (Caspase-2 inhibitor NH-23-C2) is a potent, selective and cell-permeable endogenous caspase-2 inhibitor, does not block caspase-3 or caspase-8. |
| PC-63279 |
ML132
Caspase-1 inhibitor
|
ML132 (NCGC-00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM, displays >1,000-fold selectivity over a panel of 9 caspases.. |
| PC-43410 |
BOC-D-FMK
Caspase inhibitor
|
BOC-D-FMK is a cell-permeable, irreversible, broad spectrum caspase inhibitor, inhibits apoptosis stimulated by TNF-α with IC50 of 39 uM. |
| PC-43391 |
VX-765
Caspase-1 inhibitor
|
VX-765 (Belnacasan) is an orally absorbed prodrug of VRT-043198, which is a potent and selective inhibitor of interleukin-converting enzyme/caspase-1 with Ki of 0.8 nM. |
| PC-43046 |
Z-DEVD-FMK
Caspase-3 inhibitor
|
Z-DEVD-FMK is a specific caspase-3 inhibitor with IC50 of 18 uM, inhibits apoptosis. |
| PC-42968 |
Q-VD-Oph
pan-Caspase inhibitor
|
Q-VD-Oph is a potent pan-caspase inhibitor, inhibits human recombinant caspase-7 with IC50 of 48 nM in cell-free assay, also inhibits caspase -1, 3, 8, 9, 10, and 12 with IC50 of 25-400 nM. |
| PC-62433 |
Emricasan
Caspase inhibitor
|
Emricasan (IDN-6556, PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity. |
| PC-62211 |
WF-210
Procaspases-3 activator
|
WF-210 is a PAC-1 derivative and potent activator of procaspases-3 with EC50 of 0.95 uM, displays more cytotoxic than PAC‐1 to human cancer cells, but less cytotoxic to normal cells. |
