Ac-LESD-AMC | Caspase-8 substrate | Probechem Biochemicals

Chemical Structure : Ac-LESD-AMC

Ac-LESD-AMC (N-acetyl-Leu-Glu-Ser-Asp-aminomethylcoumarin)

Catalog No.: PC-27874Not For Human Use, Lab Use Only.

Ac-LESD-AMC is a caspase-8 fluorogenic substrate (relative Kcat/K M = 0.15) that most efficiently hydrolyzed by caspase-8 and caspase-10, 10-fold faster than inflammatory caspases-1, -4, and -5.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

Ac-LESD-AMC is a caspase-8 fluorogenic substrate (relative Kcat/K M = 0.15) that most efficiently hydrolyzed by caspase-8 and caspase-10, 10-fold faster than inflammatory caspases-1, -4, and -5.

Physicochemical Properties

M.Wt	661.67
Formula	C30H39N5O12
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4S,7S,10S,13S)-7-(2-carboxyethyl)-10-(hydroxymethyl)-4-isobutyl-13-((4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl)-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid

References

1. Bourne CM, et al. ACS Bio Med Chem Au. 2025 Jul 2;5(4):565-581.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

Ac-LESD-AMC (N-acetyl-Leu-Glu-Ser-Asp-aminomethylcoumarin)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.