| Cat. No. |
Product Name |
Information |
| PC-23805 |
FLIPinBγ
c-FLIPL inhibitor
|
FLIPinBγ is a first-in class, specific small molecule inhibitor of c-FLIPL in the caspase-8/c-FLIPL heterodimer, promotes CD95L- and TRAIL-mediated loss of cell viability and cell death. |
| PC-22972 |
Pralnacasan
Caspase-1 inhibitor
|
Pralnacasan (VX-740) is a potent, selective, non-peptide and orally active caspase 1 (interleukin-1β converting enzyme, ICE) inhibitor with Ki of 1.4 nM, inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. |
| PC-22751 |
Z-YVAD-FMK
Caspase-1 inhibitor
|
Z-YVAD-FMK is a specific, cell-permeable and irreversible caspase-1 inhibitor with anti-inflammatory and anti-tumor activities. |
| PC-22034 |
CZL80
Caspase-1 inhibitor
|
Caspase-1 inhibitor CZL80 is a potent, selective, brain‐penetrable Caspase-1 inhibitor with IC50 of 0.01 uM. |