Caspase compound (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-22972	Pralnacasan Caspase-1 inhibitor	Pralnacasan (VX-740) is a potent, selective, non-peptide and orally active caspase 1 (interleukin-1β converting enzyme, ICE) inhibitor with Ki of 1.4 nM, inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ.
PC-22751	Z-YVAD-FMK Caspase-1 inhibitor	Z-YVAD-FMK is a specific, cell-permeable and irreversible caspase-1 inhibitor with anti-inflammatory and anti-tumor activities.
PC-22740	Procaspase-3 activator PAC‐1 Procaspase-3 activator	PAC-1 is a small-molecule activator of procaspase-3 to caspase-3, induces apoptosis in cancerous cells, induces apoptosis in HL-60 cells with EC50 of 2.08 uM.
PC-22034	CZL80 Caspase-1 inhibitor	Caspase-1 inhibitor CZL80 is a potent, selective, brain‐penetrable Caspase-1 inhibitor with IC50 of 0.01 uM.

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