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KEA1-97

Chemical Structure : KEA1-97

CAS No.: 2138882-71-8

KEA1-97 (KEA 1-97)

Catalog No.: PC-60171Not For Human Use, Lab Use Only.

KEA1-97 (KEA 1-97) is a small molecule that disrupts the interaction of thioredoxin with caspase 3.

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25 mg $168 In stock
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100 mg $498 In stock
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Biological Activity

KEA1-97 (KEA 1-97) is a small molecule that disrupts the interaction of thioredoxin with caspase 3.
KEA1-97 activates caspases, and induces apoptosis without affecting thioredoxin activity, impairs triple-negative breast cancer cell survival.
KEA1-97 impairs in vivo breast tumor xenograft growth.

Physicochemical Properties

M.Wt 335.163
Formula C15H9Cl2FN4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 100 mg/mL

Chemical Name/SMILES

4,6-dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine

References

1. Anderson KE, et al. ACS Chem Biol. 2017 Oct 20;12(10):2522-2528.

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