KEA1-97 | Thioredoxin-Caspase 3 inhibitor

Chemical Structure : KEA1-97

CAS No.: 2138882-71-8

KEA1-97 (KEA 1-97)

Catalog No.: PC-60171Not For Human Use, Lab Use Only.

KEA1-97 (KEA 1-97) is a small molecule that disrupts the interaction of thioredoxin with caspase 3.

Packing	Price	Stock
10 mg	$78	In stock
25 mg	$128	In stock
50 mg	$218	In stock
100 mg		Get quote

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Biological Activity

KEA1-97 (KEA 1-97) is a small molecule that disrupts the interaction of thioredoxin with caspase 3.
KEA1-97 activates caspases, and induces apoptosis without affecting thioredoxin activity, impairs triple-negative breast cancer cell survival.
KEA1-97 impairs in vivo breast tumor xenograft growth.

Physicochemical Properties

M.Wt	335.163
Formula	C15H9Cl2FN4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: 100 mg/mL
Chemical Name/SMILES	4,6-dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine

References

1. Anderson KE, et al. ACS Chem Biol. 2017 Oct 20;12(10):2522-2528.

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KEA1-97 (KEA 1-97)

Biological Activity

Physicochemical Properties

References

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